研究業績

学術論文

2026年

• Arsenite sensitizes to ferroptosis by disrupting selenium metabolism and reducing GPx4 expression

  Takashima, H.#, Makino, R.#, Taguchi, H., Ito, J., Mishima, E., Takenaka, Y., Akiyama, Y., Sumi, D., Conrad, M., Tomikoka, Y., Toyama, T.*, Saito, Y.* #equally contribution

  Toxicology, 522, 154409 (2026).

  • DOI: https://doi.org/10.1016/j.tox.2026.154409
• Tocotrienols exhibit superior ferroptosis inhibition over tocopherols

  Yang, H.#, Ito, J.#*, Maejima, T., Kimura, S., Ino, H., Hirata, Y., Matsuzawa, A., Kobayashi, S., Mishima, E.*, Nakagawa, K. #equally contribution

  Scientific Reports, accepted for publication (2026).

  • DOI: https://www.nature.com/articles/s41598-025-34673-1
• A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

  Lorenz, S.M.#, Wahida, A.#, Bostock, M.J.#, Seibt, T.#, Mourão, A.S.D.#, Levkina, A., Trümbach, D., Soudy, M., Emler, D., Rothammer, N., Woo, M.S., Sonner, J.K., Novikova, M., Henkelmann, B., Aldrovandi, M., Kaemena, D.F., Mishima, E., Vermonden, P., Zong, Z., Cheng, D., Nakamura, T., Ito, J., Doll, S., Proneth, B., Bürkle, E., Rizzollo, F., Escamilla Ayala, A., Napolitano, V., Kolonko-Adamska, M., Gaussmann, S., Merl-Pham, J., Hauck, S., Pertek, A., Orschmann, T., van San, E., Vanden Berghe, T., Hass, D., Maida, A., Frenz, J.M., Pedrera, L., Dolga, A., Kraiger, M., Hrabé de Angelis, M., Fuchs, H., Ebert, G., Lenberg, J., Friedman, J., Scale, C., Agostinis, P., Zimprich, A., Vogt-Weisenhorn, D., Garrett, L., Hölter, S.M., Wurst, W., Glaab, E., Lewerenz, J., Popper, B., Sieben, C., Steinacker, P., Zischka, H., Garcia-Saez, A.J., Tietze, A., Ramesh, S.K., Ayton, S., Vincendeau, M., Friese, M.A., Wigby, K., Sattler, M., Mann, M., Ingold, I., Jayavelu, A.K., Popowicz, G.M., Conrad, M.*

  Cell, 189, 287-306 (2026).

  #equally contribution

  • DOI: 10.1016/j.cell.2025.11.014
• Zinc-MTF1-metallothionein axis plays critical roles in the defense against ferroptosis in human cells

  Wagatsuma, T., Yamamoto, A., Nishimura, Y., Kawami, M., Ito, J., Hirayama, T., Masuda, S., Nakagawa, K., Uchida, Y., Kambe, T.*

  Free Radical Biology and Medicine (2026).

  • DOI: 10.1016/j.freeradbiomed.2026.01.008

2025年

• The role of redoxins in ferroptosis

  Ito, J., Lillig, C., Berndt, C.*

  Ferroptosis and Oxidative Stress, 1, 202515 (2025).

  • DOI: 10.70401/fos.2025.0008
• FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis

  Lange, M., Wölk, M., Li, V. W., Doubravsky, C. E., Hendricks, J. M., Kato, S., Otoki, Y., Styler, B., Johnson, S. L., Harris, C. A., Nakagawa, K., Snodgrass, I. F., Kim, D., Newman, J. W., Fedorova, M., & Olzmann, J. A.

  Nat. Cell Biol., 27, 1902–1913 (2025).

  • DOI: 10.1038/s41556-025-01790-y
• Well-to-well transfer of HaloTag ligand 6-chlorohexan-1-ol and formaldehyde in a multi-well plate

  Mishima, Yugo., Yasuda, S., Kunitomi, A., Masuda-Ozawa, T., Tomoshige, S., Kato, S., Kadono, Y., Nakagawa, K., Ishikawa, M

  Sci. Rep., 29 (2025).

  • DOI: 10.1038/s41598-025-29372-w
• Elucidating the antioxidative mechanisms by blending rice bran oil with canola oil at ambient temperature

  Koishi, S., Honda, S., Matsuki, M., Sawada, K., Hashimoto, H., Kadono, Y., Rahmania, H., Otoki, Y., Kato, S., & Nakagawa, K.*

  Food Res. Int., 221, 4, 117509 (2025).

  • DOI: 10.1016/j.foodres.2025.117509
• Effects of sodium chloride on the formation of 3-Monochloropropanediol esters in various meats and health risk assessment

  Hao-Ting Chen, Chui Xuan Tan, Jiun-Rong Chen, Kiyotaka Nakagawa, Shunji Kato, Wei-Ju Lee

  Food Chemistry: X, 29, 102754 (2025).

  • DOI: 10.1016/j.fochx.2025.102754
• Synthesis of Citrifurans A and D through Assembly of the Natural Products Citrinin and Gregatin A

  Goto, Y., Machiya, A., Okumura, T., Oka, Y., Ito, J., Ishibashi, O., Shiono, Y., Meguro, Y., Nakagawa, K., Kuwahara, S., Enomoto, M.*

  Org. Lett., 27, 30, 8349-8352 (2025).

  • DOI: 10.1021/acs.orglett.5c02665
• Relationship between the Particle Size and the Oxidative Stability of Aqueous Emulsion Prepared from Triacylglycerol Rich in Docosahexaenoic Acid

  Sato-Ishizaki, Y.*, Iguchi, A., Someya, K., Kusumoto, I., Kato, S., Nakagawa, K., Gotoh, N.

  J. Oleo Sci., 74, 8, 729-737 (2025).

  • DOI: 10.5650/jos.ess25092
• N-acetyl-l-cysteine averts ferroptosis by fostering glutathione peroxidase 4

  Zheng, J., Zhang, W., Ito, J., Henkelmann, B., Xu, C., Mishima, E., Conrad, M.*

  Cell Chem. Biol., 32, 767-775 (2025).

  • DOI: 10.1016/j.chembiol.2025.04.002
• MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4

  Mishima, E.#, O'Neill, T.J.#, Hoefig, K.P., Chen, D., Behrens, G., Henkelmann, B., Ito, J., Nakagawa, K., Heissmeyer, V.*, Conrad, M.*, Krappmann, D.*

  Proc. Natl. Acad. Sci. U.S.A., 122, e2507997122 (2025).

  • DOI: 10.1073/pnas.2507997122
• Air pollution and Alzheimer disease phenotype deplete esterified pro-resolving lipid mediator reserves in the brain

  Taha, A. Y.*, Shen, Q., Otoki, Y., Liang, N., Patten, K. T., Valenzuela, A. E., Wallis, C. D., Rowland, D. J., Chaudhari, A. J., Bein, K. J., Wexler, A. S., Jin, L.-W., Dugger, B. N., Harvey, D. J., Lein, P. J.

  JCI Insight., e175917 (2025).

  • DOI: 10.1172/jci.insight.175917
• The Therapeutic Potential of Plant-Derived Flavonoids in Neurological Disorders Through Modulation of Brain Insulin Signaling

  Parida, I.S., Rahmania, H., Nakagawa, K.*

  Food Sci. Technol. Res., 31, 75-89 (2025).

  • DOI: 10.3136/fstr.FSTR-D-24-00202
• Nondestructive determination of canola oil oxidation causes: A near-infrared spectroscopy coupled with liquid chromatography-mass spectrometry for analyzing triacylglycerol hydroperoxide isomers

  Otoki, Y.*, Ishikawa, D., Kato, S., Kusumoto, I., Ozaki, Y., Nakagawa, K.*

  Food Chem., 467, 142143 (2025).

  • DOI: 10.1016/j.foodchem.2024.142143
• Dietary Ethanolamine Plasmalogen from Ascidian Alleviates Chronic Hepatic Injury in Mice Treated with Continuous Acetaminophen

  Sogame, R., Tominaga, Y., Echigoya, M., Nakagawa, K., Fukushima, M., Miyazawa, T., Kinoshita, M., Yamashita, S.*

  Appl. Sci., 15, 5968 (2025).

  • DOI: 10.3390/app15115968
• Effect of microemulsion system on water dispersibility and bioavailability of γ-oryzanol

  Ito, J., Kumagai, N., Suzuki, A., Shoji, N., Parida, I. S., Takahashi, M., Nakagawa, K.*

  Biosci. Biotechnol. Biochem., 89, 633–637 (2025).

  • DOI: 10.1093/bbb/zbaf002

2024年

• Impact of selenium content in fetal bovine serum on ferroptosis susceptibility and selenoprotein expression in cultured cells

  Takashima, H., Toyama, T.*, Mishima, E., Ishida, K., Wang, Y., Ichikawa, A., Ito, J., Yogiashi, S., Siu, S., Sugawara, M., Shiina, S., Arisawa, K., Conrad, M., Saito, S.*

  J. Toxicol. Sci., 49, 555-563 (2024).

  • DOI: 10.2131/jts.49.555
• Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria

  Hirata Y*, Yamada Y, Taguchi S, Kojima R, Masumoto H, Kimura S, Niijima T, Toyama T, Kise R, Sato E, Uchida Y, Ito J, Nakagawa K, Taguchi T, Inoue A, Saito Y, Noguchi T, Matsuzawa A.*

  Cell Death Dis., 15, 884 (2024).

  • DOI: 10.1038/s41419-024-07237-w
• PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization

  Ito, J., Nakamura, T., Toyama, T., Chen, D., Berndt, C., Poschmann, G., Mour_o, A. S. D., Doll, S, Suzuki, M., Zhang, W., Zheng, J., Tr_mbach, D., Yamada, N., Ono, K., Yazaki, M., Kawai, Y., Arisawa, M., Ohsaki, Y., Shirakawa, H., Wahida, A., Proneth, B., Saito, Y., Nakagawa, K., Mishima, E., Conrad, M.

  Mol. Cell., 84, 4629-4644 (2024).

  • DOI: 10.1016/j.molcel.2024.10.028
• Oil polyunsaturated fatty acid composition but not tocopherol levels determine oxylipin formation in plant and algae oils during pan-frying

  Kusumoto, I., Hennebelle, M., Crawford, L. M., Wang, S. C., Taha, A. Y.*

  J. Food Compos. Anal., 136, 106739 (2024).

  • DOI: 10.1016/j.jfca.2024.106739
• Mechanism of lipid peroxidation of liposomes by cold atmospheric pressure plasma jet irradiation

  Takajo, T., Saito, K., Tsuchida, K., Kato, S., Nakagawa, K., Okino, A., Anzai, K.*

  J. Clin. Biochem. Nutr., 75, 183-189 (2024).

  • DOI: 10.3164/jcbn.24-72
• 1-Deoxynojirimycin attenuates pathological markers of Alzheimer's disease in the in vitro model of neuronal insulin resistance

  Parida, I.S., Takasu, S., Ito, J., Eitsuka, T., Nakagawa, K.*

  FASEB J., 15, e23800 (2024).

  • DOI: 10.1096/fj.202302600R
• Effects of different manufacturing processes on thermal and photo-oxidative stability of sesame oil

  Rahmania, H.#, Nakanishi, T.#, Oi, S., Onishi, R., Yamagami, E., Yamane,K., Otoki, Y., Kato, S., Nakagawa, K.*

  J. Oleo Sci., 73, 1267-1276 (2024).

  • DOI: 10.5650/jos.ess24084
• Intraperitoneally injected d11-11(12)-epoxyeicosatrienoic acid is rapidly incorporated and esterified within rat plasma and peripheral tissues but not the brain

  Watanabe, S., Souza, F. D. C., Kusumoto, I., Shen, Q., Nitin, N., Lein, P. J., Taha, A. Y.

  Prostaglandins, Leukot. Essent. Fat. Acids, 102622 (2024).
• Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis

  Yamada, N.#*, Karasawa, T.#*, Ito, J., Yamamuro, D., Morimoto, K., Nakamura, T., Komada, T., Baatarjav, C., Saimoto, Y., Jinnouchi, Y., Watanabe, K., Miura, K., Yahagi, Y., Nakagawa, K., Matsumura, T., Yamada, K., Ishibashi, S., Sata, N., Conrad M., Takahashi, M.*

  Nat. Commun., 15, 2195 (2024).
• A tangible method to assess native ferroptosis suppressor activity

  Nakamura, T.#, Ito, J.#, Mour_o, A.S.D., Wahida, A., Nakagawa, K., Mishima, E.*, Conrad, M.*

  Cell Rep. Methods, 4, 100710 (2024).
• Identification of genes associated with resistance to persulcatusin, a tick defensin from Ixodes persulcatus

  Shimoda, S., Ito, J., Ando, T., Tobe, R., Nakagawa, K., Yoneyama, H.*

  Microorganisms, 12, 412 (2024).
• Induction of ferroptosis in human keratinocyte HaCaT cells by squalene hydroperoxide: Possible prevention of skin ferroptosis by botanical extracts

  Kato, C., Kusumoto, I., Kato, S., Otoki, Y., Ito, J., Totsuka, H., Rajgopal, A., Hong, J., Nakagawa, K.*

  Biochem. Biophys. Res. Commun., 698, 149553 (2024).
• Comparison of the catabolic rates of linoleic and oleic acid hydroperoxides using 13CO2 expired from mice

  Yoshinaga-Kiriake, A., Miyagawa, S., Yoshino, K., Tanaka, S., Yoshinaga, K., Takahashi, T., Kato, S., Ito, J., Yurika, O., Nakagawa, K., Gotoh, N.*

  J. Oleo Sci. (2024).
• Preparation of saturated fatty acid hydroperoxide isomers and determination of their thermal decomposition products _ 2-alkanones and lactones

  Aoyagi, K., Kato, S., Isaka, D., Sekiguchi, Y., Otoki, Y., Uehara, H., Nakagawa, K.*

  Food Chem. X, 21, 101074 (2024).
• Higher Cholesterol Absorption Marker at Baseline Predicts Fewer Cardiovascular Events in Elderly Patients Receiving Hypercholesterolemia Treatment: The Kyushu Elderly Ezetimibe Phytosterol (KEEP) Study

  Kuwabara, M., Sasaki, J., Ouchi, Y., Oikawa, S., Nakagawa, K., Sato, M., Koba, S., Kono, S., Saikawa, T., Arai, H.*

  J. Am. Heart Assoc., 13, e03165 (2024).
• LC-MS/MS analysis of milk triacylglycerol hydroperoxide isomers which are generated corresponding to the photo- and thermal-oxidation

  Saito, H., Kato, S., Shimizu, N., Takahashi, T., Jutanom, M., Ito, J., Kasatani, S., Nakagawa, K.*

  Food Res. Int., 178, 113913 (2024).

2023年

• Analysis of oxidized glucosylceramide and its effects on altering gene expressions of inflammation induced by LPS in intestinal tract cell models

  Jutanom, M., Kato, S., Yamashita, S., Toda, M., Kinoshita, M., Nakagawa, K.*

  Sci. Rep., 13, 22537 (2023).
• Unveiling an unexpected superoxide-mediated photooxidation mechanism of squalene monohydroperoxides to squalene hydroperoxy cyclic peroxides through ESR and LC_MS/MS analyses

  Khalifa, S., Enomoto, M., Nakagawa, K.*

  Sci. Rep., 13, 19525 (2023).
• Sheep-derived cell immortalization through the expression of cell cycle regulators and biological characterization using transcriptomes

  Kikuchi, N., Matsusaka, H., Bai, L., Sano, H., Eitsuka, T., Nakagawa, K., Sugano, E., Ozaki, T., Tomita, H., Kiyono, T., Fukuda, T.*

  Cell Biol. Int. (2023).
• The difference in the cellular uptake of tocopherol and tocotrienol is influenced by their affinities to albumin

  Nakatomi, T., Itaya-Takahashi, M., Horikoshi, Y., Shimizu, N., Parida, I.S., Jutanom, M., Eitsuka, T., Tanaka, Y., Zingg, J.-M., Matsura, T., Nakagawa K.*

  Sci. Rep., 13, 7392 (2023).
• Expression and functional analyses for estrogen receptor and estrogen related receptor of Yesso scallop, Patinopecten yessoensis

  Gu, W., Thitiphuree, T., Otoki, Y., Marquez, E.C., Kitano, T., Itoh, N., Nagasawa, K., Osada, M.

  J. Steroid Biochem. Mol., 106302 (2023).
• Immortalization of primary cells derived from the endangered Ryukyu long-furred rat

  Bai, L., Kikuchi, N., Eitsuka, T., Matsusaka, H., Nakagawa, K., Katayama, M., Ito, K., Inoue-Murayama, M., Kiyono,T., Fukuda, T.*

  In Vitro Cellular & Developmental Biology - Animal, 59, 224-233 (2023).
• ホヤ由来エタノールアミン型プラズマローゲンの認知機能に対する有効性及び安全性評価―プラセボ対照ランダム化二重盲検並行群間比較―

  山本采佳*, 相澤光輝, 久保村大樹, 赤堀雄介, 山下慎司, 仲川清隆, 宮澤陽夫

  応用薬理, 104, 17-24 (2023).
• コーヒーシルバースキンに含まれる3-ピリジノールの単離精製とメラニン産生に及ぼす影響

  渡辺章夫, 衛藤未侑, 小山彩華, 要害心, 保永陽依, 前原一葉, 宮本京香, 加藤毅, 三嶋隆, 仲川清隆

  十文字大学紀要, 53, 29-36 (2023).
• Quantitative lipidomic analysis of serum phospholipids reveals dissociable markers of Alzheimer disease and subcortical cerebrovascular disease

  Otoki, Y., Yu, D., Shen, Q., Sahlas, D.J., Ramirez, J., Gao, F., Masellis, M., Swartz, R.H., Chan, P.C., Pettersen, J.A., Kato, S., Nakagawa, K., Black, S.E., Swardfager, W., Taha, A.T.*

  J. Alzheimer's Dis., 93, 665-682 (2023).
• Effects of particle size of curcumin solid dispersions on bioavailability and anti-inflammatory activities

  Kato, C., Itaya-Takahashi, M., Miyazawa, T., Ito, J., Parida, I.S., Yamada, H., Abe, A., Shibata, M., Someya, K., Nakagawa,K.*

  Antioxidants, 12, 724 (2023).
• Elucidation of decomposition pathways of linoleic acid hydroperoxide isomers by GC-MS and LC-MS/MS

  Miyazaki, R., Kato, S., Otoki, Y., Rahmania, H., Sakaino, M., Takeuchi, S., Sato, T., Imagi, J., Nakagawa, K.*

  Biosci. Biotechnol. Biochem., 87, 179-190 (2023).
• Clinical evaluation based on a new approach to improve the accuracy of 4β-hydroxycholesterol measurement as a biomarker of CYP3A4 activity

  Taya, Y. Mizunaga, M., Nakao, S., Jutanom, M., Shimizu, N., Nomura, Y., Nakagawa,K.*

  Molecules, 28, 1576 (2023).
• Analysis of docosahexaenoic acid hydroperoxide isomers in mackerel using liquid chromatography_mass spectrometry

  Kusumoto, I., Kato, S., Nakagawa, K.*

  Sci. Rep., 13, 1325 (2023).

2022年

• Evidence of increased sequestration of pro-resolving lipid mediators within brain esterified lipid pools of multiple sclerosis patients

  Shen, Q., Otoki, Y., Sobel, R.A., Nagra, R.M., Taha, A.Y.*

  Mult . Scler. Relat. Disord., 68, 104236 (2022).
• Structural analysis and anti-inflammatory effect of a digalactosyldiacylglycerol-monoestolide, a characteristic glycolipid in oats

  Yamada, H., Ito, J., Shimizu, N., Takahashi, T., Kato, C., Parida, I.S., Jutanom, M., Ishihara, K., Nakagawa,K.*

  Nutrients, 14, 4153 (2022).
• Coprinopsis cinerea dioxygenase is an oxygenase forming 10(S)-hydroperoxide of linoleic acid, essential for mushroom alcohol, 1-octen-3-ol synthesis

  Teshima, T., Funai, R., Nakazawa, T., Ito, J., Utsumi, T., Kakumyan, P., Mukai, H., Yoshiga, T., Murakami, R., Nakagawa, K., Honda, Y., Matsui, K.*

  J. Biol. Chem., 298, 102507 (2022).
• Dietary triacylglycerol hydroperoxide is not absorbed, yet it induces the formation of other triacylglycerol hydroperoxides in the gastrointestinal tract

  Takahashi, T., Kato, S., Ito, J., Shimizu, N., Parida, I.S., Itaya-Takahashi, M., Sakaino, M., Imagi, J., Yoshinaga, K., Yoshinaga-Kiriake, A., Gotoh, N., Ikeda. I., Nakagawa, K.*

  Redox. Biol., 57, 102471 (2022).
• Possible Glutathione Peroxidase 4-Independent Reduction of Phosphatidylcholine Hydroperoxide: Its Relevance to Ferroptosis

  Kato, C., Suzuki, Y., Parida, I.S., Kato, S., Yamasaki, H., Takekoshi, S., Nakagawa, K.*

  J. Oleo Sci., 71, 1689-1694 (2022).
• Cellular uptake of pyrroloquinoline quinone in its intact and derivatized forms from the cell culture medium of 3T3-L1

  Kato, C., Parida, I.S., Maeda, S., Mikekado, T., Kato, S., Takekoshi, S., Nakagawa, K.*

  J. Oleo Sci., 71, 1761-1767 (2022).
• A non-canonical vitamin K cycle is a potent ferroptosis suppressor

  Mishima, E.*, Ito, J., Wu, Z., Nakamura, T., Wahida, A., Doll, S., Tonnus, W., Nepachalovich, P., Eggenhofer E., Aldrovandi, M., Henkelmann, B., Yamada, K., Wanninger, J., Zilka, O., Sato, E., Feederle, R., Hass, D., Maida, A., Mour_o, A.S.D., Linkermann, A., Geissler, E.K., Nakagawa, K., Abe, T., Fedorova, M., Proneth, B., Pratt, D.A., Conrad, M.*

  Nature, 608, 778-783 (2022).
• Determination of olive oil oxidation mechanisms by analysis of triacylglycerol hydroperoxide isomers using LC-MS/MS

  Takahashi, H., Kato, S., Shimizu, N., Otoki, Y., Ito, J., Sakaino, M., Sano, T., Imagi, J., Nakagawa, K.*

  Molecules, 27, 5282 (2022).
• Carboxylic acids derived from triacylglycerols that contribute to the increase in acid value during the thermal oxidation of oils

  Sakaino, M., Sano, T., Kato, S., Shimizu, N., Ito, J., Rahmania, H., Imagi, J., Nakagawa, K.*

  Sci. Rep., 12, 12460 (2022).
• Total synthesis of the broad-spectrum antibiotic amycolamicin

  Meguro, Y., Ito, J., Nakagawa, K., Kuwahara, S.*

  J. Am. Chem. Soc., 144, 5253-5257 (2022).
• Improving water dispersibility and bioavailability of luteolin using microemulsion system

  Miyashita, A., Ito, J., Parida, I.S., Syoji, N., Fujii, T., Takahashi, H., Nakagawa, K.*

  Sci. Rep., 12, 11949 (2022).
• Immortalization of common marmoset-derived fibroblasts via expression of cell cycle regulators using the piggyBac transposon

  Orimoto, A.*, Shinohara, H. Eitsuka, T., Nakagawa, K., Sasaki, E., Kiyono, T.*, Fukuda, T.*

  Tissue Cell, 77, 101848 (2022).
• Cellular concentrations of plasmalogen species containing a polyunsaturated fatty acid significantly increase under hypoxia in human colorectal cancer, Caco2 cells

  Tamiya-Koizumi, K., Otoki, Y., Nakagawa, K., Kannagi, R., Mizutani, N., Suzuki, M., Kyogashima, M., Iwaki, S., Aoyama, M., Murate, T., Kitatani, K., Kuga, T., Mizutani, Y., Tokumura, A.*

  Biochem. Biophys. Res. Commun., 611, 1-7 (2022).
• Effects of hypercapnia / ischemia and dissection on the rat brain metabolome

  Sylvestre, D.A., Otoki, Y., Metherel, A.H., Bazinet, R.P., Slupsky, C.M. Taha. A.Y.*

  Neurochem. Int., 156, 105294 (2022).
• Determination of acrolein generation pathways from linoleic acid and linolenic acid: increment by photo irradiation

  Kato, S., Shimizu, N., Otoki, Y., Ito, J., Sakaino, M. Sano, T., Takeuchi, S., Imagi, J., Nakagawa, K.*

  npj Sci. Food, 6, 21 (2022).
• Lipidomics and redox lipidomics indicate early-stage alcohol-induced liver damage

  Koelmel, J.P., Tan, W.Y., Li, Y., Bowden, J.A., Ahmadireskety, A., Patt, A.C., Orlicky, D.J., Math_, E., Kroeger, N.M., Thompson, D.C., Cochran, J.A., Golla, J.P., Kandyliari, A., Chen, Y., Charkoftaki, G., Guingab-Cagmat, J.D., Tsugawa, H., Arora, A., Veselkov, K., Kato, S., Otoki, Y., Nakagawa, K., Yost, R.A., Garrett, T.J.*, Vasilou, V.*

  Hepatol. Commun., 6, 513-525 (2022).
• The inhibition of interaction with serum albumin enhances the physiological activity of curcumin by increasing its cellular uptake

  Itaya, M., Miyazawa, T., Khalifa, S., Shimizu N., Nakagawa, K.*

  Food Funct., 13, 639-648 (2022).